Between Madrid and Prague we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Madrid or from Madrid to larger cities near Prague.
Traveling by bus from Madrid to Prague
The shortest travel distance between Madrid (ES) and Prague (CZ) is 2313 km, which equals a travel time by car of about 21:20 h.
Departure and arrival station
You can see information about the departure station and stops Madrid here
You can see information about the arrival station and stops Prague here