Between Madrid and Brussels we found up to 4
including 4 night buses.
The earliest departure from Madrid is at 14:00 arriving to Brussels at 10:15.
The latest departure is at 22:30 arriving at 20:15.
Prices for a one way adult ticket range from 49 € to 99 €.
10:15Brussels RUE DU PROGRÈS, NORTH STATION / Noordstation
Best offer on 28. Feb
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Traveling by bus from Madrid to Brussels
The shortest travel distance between Madrid (ES) and Brussels (BE) is 1580 km.
The fastest bus which departs at 14:00 has a travel time of 20:15h.
The longest travel time on the route is 22:35h.
Specific information about each route can be found by clicking the route in the search results.
Overnight bus Madrid to Brussels
If you want to travel overnight, there are 4 night buses from Madrid to Brussels.
The overnight buses depart between 14:00 and 22:30 and arrive between 10:15 and 20:15 in the morning.