Between Prague and Madrid we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Prague or from Prague to larger cities near Madrid.
Traveling by bus from Prague to Madrid
The shortest travel distance between Prague (CZ) and Madrid (ES) is 2313 km, which equals a travel time by car of about 21:29 h.
Departure and arrival station
You can see information about the departure station and stops Prague here
You can see information about the arrival station and stops Madrid here