Between Santander and Madrid we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Santander or from Santander to larger cities near Madrid.
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Traveling by bus from Santander to Madrid
The shortest travel distance between Santander (ES) and Madrid (ES) is 456 km, which equals a travel time by car of about 04:23 h.
Departure and arrival station(s)
You can see information about the departure station and stops Santander here
You can see information about the arrival station and stops Madrid here