Between Santander and Brussels we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Santander or from Santander to larger cities near Brussels.
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Traveling by bus from Santander to Brussels
The shortest travel distance between Santander (ES) and Brussels (BE) is 1317 km, which equals a travel time by car of about 12:29 h.
Departure and arrival station(s)
You can see information about the departure station and stops Santander here
You can see information about the arrival station and stops Brussels here