Between Madrid and Orihuela we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Madrid or from Madrid to larger cities near Orihuela.
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Traveling by bus from Madrid to Orihuela
The shortest travel distance between Madrid (ES) and Orihuela (ES) is 423 km, which equals a travel time by car of about 04:01 h.
Departure and arrival station(s)
You can see information about the departure station and stops Madrid here
You can see information about the arrival station and stops Orihuela here