Between Lyon and Siena we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Lyon or from Lyon to larger cities near Siena.
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Traveling by bus from Lyon to Siena
The shortest travel distance between Lyon (FR) and Siena (IT) is 795 km, which equals a travel time by car of about 08:24 h.
Departure and arrival station(s)
You can see information about the departure station and stops Lyon here
You can see information about the arrival station and stops Siena here