Between Lyon and Prague we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Lyon or from Lyon to larger cities near Prague.
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Traveling by bus from Lyon to Prague
The shortest travel distance between Lyon (FR) and Prague (CZ) is 1079 km, which equals a travel time by car of about 10:41 h.