Between Calais and Lyon we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Calais or from Calais to larger cities near Lyon.
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Traveling by bus from Calais to Lyon
The shortest travel distance between Calais (FR) and Lyon (FR) is 762 km, which equals a travel time by car of about 06:56 h.