Between Rome and Alessandria we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Rome or from Rome to larger cities near Alessandria.
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Traveling by bus from Rome to Alessandria
The shortest travel distance between Rome (IT) and Alessandria (IT) is 610 km, which equals a travel time by car of about 06:00 h.