Between Frankfurt and Prague we found up to 8 bus departures, including 3 night buses. The earliest departure from Frankfurt is at 00:15 arriving to Prague at 07:25. The latest departure is at 23:25 arriving at 31:25. Prices for a one way adult ticket range from 25 € to 56 €.
The shortest travel distance between Frankfurt (DE) and Prague (CZ) is 519 km. The fastest bus which departs at 07:15 has a travel time of 06:20h. The longest travel time on the route is 08:55h. Specific information about each route can be found by clicking the route in the search results.
If you want to travel overnight, there are 3 night buses from Frankfurt to Prague. The overnight buses depart between 23:15 and 23:25 and arrive between 06:28 and 31:25 in the morning.
You can see information about the departure station and stops Frankfurt here
You can see information about the arrival station and stops Prague here
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