Between Frankfurt and Lisbon we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Frankfurt or from Frankfurt to larger cities near Lisbon.
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Traveling by bus from Frankfurt to Lisbon
The shortest travel distance between Frankfurt (DE) and Lisbon (PT) is 2319 km, which equals a travel time by car of about 20:43 h.