Between Alexandroupoli and Istanbul we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Alexandroupoli or from Alexandroupoli to larger cities near Istanbul.
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Traveling by bus from Alexandroupoli to Istanbul
The shortest travel distance between Alexandroupoli (GR) and Istanbul (TR) is 305 km, which equals a travel time by car of about 03:42 h.