Santiago to La Serena Bus: Book Your Seat for Less

Santiago to La Serena La Serena to Santiago

Between Santiago and La Serena we found over 50 bus departures, including 29 night buses. The earliest bus departure from Santiago is at 07:50 arriving to La Serena at 14:00 the same day. While the latest bus departure is at 23:59 and arrives at 06:29 the following day. Prices for a one way adult ticket range from $12 to $28.

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Table Of Contents

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Popular Departures

Below you will find some of the most popular bus departures from Santiago to La Serena:

USD

Timetable: TODAY TOMORROW

08:00 Santiago

7h 15min

15:15 La Serena

from  16.92   HRK

Best offer on 15. Jul

pick a date

08:50 Santiago

6h 10min

15:00 La Serena

from  12.77   HRK

Best offer on 15. Jul

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09:30 Santiago

6h 15min

15:45 La Serena

from  16.92   HRK

Best offer on 15. Jul

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10:00 Santiago

6h 50min

16:50 La Serena

from  16.92   HRK

Best offer on 15. Jul

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11:00 Santiago

6h 45min

17:45 La Serena

from  16.92   HRK

Best offer on 15. Jul

pick a date

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Traveling by bus from Santiago to La Serena

The shortest travel distance between Santiago and La Serena is 294 mi. The fastest bus which departs at 09:00 has a travel time of 05:30h. The longest travel time on the route is 07:15h. Depending on the selected departure, the following amenities are available: air condition, wifi and restroom.

Overnight buses

If you want to travel overnight and save money on accommodation or arrive in La Serena earlier, there are 29 overnight buses from Santiago to La Serena. The overnight buses depart between 18:00 and 23:59 and arrive between 00:30 and 06:29 the following day. Below are the most popular night departures to La Serena:

USD

Timetable: TODAY TOMORROW

18:30 Santiago

7h 15min

01:45 La Serena

from  16.92   HRK

Best offer on 15. Jul

pick a date

19:00 Santiago

6h 10min

01:10 La Serena

from  12.77   HRK

Best offer on 15. Jul

pick a date

20:00 Santiago

6h 25min

02:25 La Serena

from  16.92   HRK

Best offer on 15. Jul

pick a date

20:00 Santiago

6h 10min

02:10 La Serena

from  12.77   HRK

Best offer on 15. Jul

pick a date

20:30 Santiago

6h 0min

02:30 La Serena

from  16.92   HRK

Best offer on 15. Jul

pick a date

Bus companies

Andesmar is the name of the company operating this route. This company has not been rated yet.

Departure and arrival stations

If you're wanting more detailed information about either Santiago or La Serena, including general information, station and stop information and other popular routes, you can follow the links below.

  Santiago

Click here to open location in google maps.

  La Serena

Click here to open location in google maps.

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Cheapest ticket prices

Adult ticket: $12 (One-Way) or $24 (Return).

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Trip reviews from Santiago to La Serena

Leave a review

If you had travelled from Santiago to La Serena, and you want to share your travel experience with fellow travellers, we encourage you to leave a review for the route and tell both to us and to other passengers what part of your journey was the best, and what needs improvement.

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Other popular destinations from Santiago

If you're wondering what other places you can visit when traveling from Santiago, these are some of the most popular combinations that other clients have purchased their tickets for:

Santiago to Mendoza

Santiago to Buenos Aires

Santiago to Chillán

Santiago to Valparaíso

Santiago to Vina del Mar

Santiago to Temuco

Santiago to Pucón

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Frequently asked questions

What is the distance between Santiago and La Serena?

What is the average travel time between Santiago and La Serena?

What is the ticket price for the journey from Santiago to La Serena?

How many daily departures are there from Santiago to La Serena?

Are all the buses direct on the route from Santiago to La Serena?

What are the amenities available on the buses departing from Santiago to La Serena?