La Serena to Santiago Bus: Book Your Seat for Less

Q: What is the distance between La Serena and Santiago?

The distance between these two places is a total of 294 mi.

Q: What is the average travel time between La Serena and Santiago?

The average travel time between the stations is 06:10 hours.

Q: What is the ticket price for the journey from La Serena to Santiago?

The ticket prices begin from $16. Some routes also offer various discounts, so you can click on a route in the search results and all discounts will be visible there.

Q: How many daily departures are there from La Serena to Santiago?

The average number of daily departures is 50. However, we would advise you to look up specific dates you're interested in so that you make sure to check the number of departures on the travel date you are interested in the most.

Q: Are all the buses direct on the route from La Serena to Santiago?

The majority of the buses are direct buses, and if there is a layover, you will see a notice on the website and there will be an icon indicating that there is a layover involved.

Q: What are the amenities available on the buses departing from La Serena to Santiago?

All the buses have air conditioning, reclining seats, luggage storage and they make breaks along the way to ensure all the passengers get enough resting time and can make a toilet break.

La Serena to Santiago Santiago to La Serena

La Serena to Santiago bus is a popular way of traveling. We found up to 71 bus departures, including 9 night buses. The earliest bus departs from La Serena at 01:50h, arriving at Santiago at 08:00h the same day. While the latest bus departs at 13:50h, arriving at 20:00h the same day.

Popular Departures

Below you will find some of the most popular bus departures from La Serena to Santiago:

Timetable: TODAY TOMORROW

01:50 La Serena

6h 10min

08:00 Santiago

from 20.43 HRK

Best offer on 23. Dec

pick a date

02:20 La Serena

6h 10min

08:30 Santiago

from 15.32 HRK

Best offer on 23. Dec

pick a date

02:50 La Serena

6h 10min

09:00 Santiago

from 20.43 HRK

Best offer on 23. Dec

pick a date

04:20 La Serena

6h 10min

10:30 Santiago

from 15.32 HRK

Best offer on 23. Dec

pick a date

09:00 La Serena

6h 10min

15:10 Santiago

from 15.32 HRK

Best offer on 23. Dec

pick a date

Traveling by bus from La Serena to Santiago

The shortest travel distance between La Serena and Santiago is 294 mi. The fastest bus which departs at has a travel time of 06:10h. The longest travel time on the route is 06:10h.

Overnight buses

If you want to travel overnight and save money on accommodation or arrive in Santiago earlier, there is 1 night bus departing from La Serena to Santiago. The overnight bus departs at and arrives at the same day.

Departure and arrival stations

If you're wanting more detailed information about either La Serena or Santiago, including general information, station and stop information and other popular routes, you can follow the links below.

La Serena

Click here to open location in google maps.

Santiago

Click here to open location in google maps.

Cheapest ticket prices

Adult ticket: $16 (One-Way) or $32 (Return).

Trip reviews from La Serena to Santiago

Leave a review

If you had travelled from La Serena to Santiago, and you want to share your travel experience with fellow travellers, we encourage you to leave a review for the route and tell both to us and to other passengers what part of your journey was the best, and what needs improvement.

Other popular destinations from Santiago

If you're looking for inspiration as to where to travel next once you've reached Santiago, here is the list of the most popular travel combinations that our clients have previously purchased their tickets for:

Santiago to Mendoza

Santiago to Buenos Aires

Santiago to Chillán

Santiago to Valparaíso

Santiago to Vina del Mar

Santiago to Temuco

Santiago to Pucón

La Serena to Santiago Bus Summary

Route Overview	Key Info
Departure Station	La Serena
Destination Station	Santiago
Daily Departures	Over 71 bus departures , including more than 9 night buses.
Earliest Departures	01:50 AM
Latest Departure	01:50 PM
Travel Distance	294 mi
Travel Time	06:10

Frequently asked questions

What is the distance between La Serena and Santiago?

What is the average travel time between La Serena and Santiago?

What is the ticket price for the journey from La Serena to Santiago?

How many daily departures are there from La Serena to Santiago?

Are all the buses direct on the route from La Serena to Santiago?

What are the amenities available on the buses departing from La Serena to Santiago?

La Serena to Santiago Bus: Book Your Seat for Less

Table Of Contents

Popular Departures

Traveling by bus from La Serena to Santiago

Overnight buses

Departure and arrival stations

Cheapest ticket prices

Trip reviews from La Serena to Santiago

Other popular destinations from Santiago

La Serena to Santiago Bus Summary

Frequently asked questions

Latest tickets bought

Getbybus guides

Latest blog posts

Latest reviews

You can pay for your tickets using credit cards