Between Karlsruhe and Skopje we found 0 direct bus departures, if connection travel options are available you can find them listed below.
Alternatively we recommend that you search for buses from larger cities near Karlsruhe or from Karlsruhe to larger cities near Skopje.
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Traveling by bus from Karlsruhe to Skopje
The shortest travel distance between Karlsruhe (DE) and Skopje (MK) is 1671 km, which equals a travel time by car of about 16:14 h.