Between Frankfurt and Lucerne we found 0 direct bus departures, if connection travel options are available you can find them listed below. Alternatively we recommend that you search for buses from larger cities near Frankfurt or from Frankfurt to larger cities near Lucerne.
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Traveling by bus from Frankfurt to Lucerne
The shortest travel distance between Frankfurt (DE) and Lucerne (CH) is 422 km, which equals a travel time by car of about 04:13 h.